Acute generalized exanthematous pustulosis induced by duloxetine

نویسندگان

چکیده

Duloxetine is a serotonin and norepinephrine reuptake inhibitor. Some rare duloxetine-induced hypersensitivity skin reactions have been reported. We report case of acute generalized exanthematous pustulosis potentially induced by duloxetine. Skin pustules appeared 8 days after the introduction Treatment with topical clobetasol propionate led to gradual remission lesions. As there are no cases pustulosis(AGEP) in literature, we did research World Health Organization (WHO) pharmacovigilance database (21 March 2022) found three AGEP. The French causality assessment score for our AGEP was 15 (C2S3). Naranjo 7, indicating possible correlation between use This consistent WHO score. inform clinicians possibility following therapy

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ژورنال

عنوان ژورنال: JEADV Clinical Practice

سال: 2023

ISSN: ['2768-6566']

DOI: https://doi.org/10.1002/jvc2.138